Pyloric stenosis, often abbreviated as PS, is a medical condition that primarily affects infants. It involves the narrowing of the opening between the stomach and the small intestine, known as the pylorus. This narrowing can lead to severe symptoms, including projectile vomiting, dehydration, and weight loss. In this article, we will explore the causes, symptoms, diagnosis, and treatment options for pyloric stenosis in detail.

Pyloric Stenosis: Causes, Symptoms, Diagnosis, and Treatment (Narrowing of the Stomach Opening)

What Is Pyloric Stenosis?

Pyloric stenosis occurs when the muscle at the bottom of the stomach, called the pylorus, becomes abnormally thickened. This thickening prevents food from passing from the stomach into the small intestine. The condition typically develops in babies between two weeks and two months of age, with boys being more commonly affected than girls.

Understanding the Anatomy

  • The stomach is responsible for breaking down food before it moves into the small intestine.
  • The pylorus acts as a valve, controlling the passage of partially digested food from the stomach to the small intestine.
  • In pyloric stenosis, the thickened pylorus blocks this passage, leading to complications.

Causes of Pyloric Stenosis

The exact cause of pyloric stenosis remains unknown, but several factors are believed to contribute to its development.

Possible Genetic Factors

Research suggests that genetics may play a role in the development of pyloric stenosis. Babies with a family history of the condition are at a higher risk. If one child in a family has been diagnosed with pyloric stenosis, the likelihood of another sibling developing the condition increases.

Hormonal Influctions

Hormones such as gastrin, which regulate stomach acid production, may also be involved. Abnormal levels of these hormones could lead to excessive growth of the pyloric muscle.

Environmental Factors

Some studies suggest that environmental factors, such as exposure to certain medications during pregnancy or early infancy, might increase the risk of pyloric stenosis. However, more research is needed to confirm these findings.

Symptoms of Pyloric Stenosis

The symptoms of pyloric stenosis usually appear within the first few weeks of life. They can vary in severity but often include the following:

Projectile Vomiting

One of the hallmark symptoms of pyloric stenosis is projectile vomiting. This type of vomiting is forceful and can project several feet away from the baby. It typically occurs shortly after feeding and may worsen over time.

Dehydration

Due to frequent vomiting, babies with pyloric stenosis may become dehydrated. Signs of dehydration include dry mouth, fewer wet diapers, sunken eyes, and lethargy.

Hunger Despite Vomiting

Despite vomiting frequently, babies with pyloric stenosis often remain hungry. They may cry for food soon after vomiting, as their bodies are not receiving adequate nutrition.

Weight Loss or Failure to Gain Weight

Babies with pyloric stenosis may experience weight loss or fail to gain weight as expected. This is due to the inability of the stomach to pass food into the intestines for digestion and absorption.

Visible Peristalsis

In some cases, parents or caregivers may notice visible waves of stomach contractions as the body attempts to push food through the narrowed pylorus. These contractions can sometimes be seen moving across the baby’s abdomen.

Diagnosis of Pyloric Stenosis

Early diagnosis of pyloric stenosis is crucial to prevent complications such as severe dehydration and malnutrition. Several diagnostic methods are used to confirm the condition.

Physical Examination

A healthcare provider will perform a thorough physical examination. During the exam, they may feel an olive-shaped lump in the baby’s abdomen, which corresponds to the thickened pylorus muscle.

Ultrasound Imaging

An ultrasound is the most common diagnostic tool for pyloric stenosis. This imaging technique uses sound waves to create pictures of the internal organs. An ultrasound can clearly show the thickened pylorus and confirm the diagnosis.

Blood Tests

Blood tests may be conducted to check for signs of dehydration and electrolyte imbalances. These tests can help assess the severity of the condition and guide treatment decisions.

Treatment Options for Pyloric Stenosis

Once diagnosed, pyloric stenosis requires prompt treatment to ensure the baby’s health and well-being. The primary treatment options include medical management and surgical intervention.

Medical Management

Before surgery, babies with pyloric stenosis may require medical stabilization. This often involves:

  • Rehydration: Intravenous fluids are administered to correct dehydration and restore electrolyte balance.
  • Nutritional Support: Once stabilized, the baby may be given small amounts of formula or breast milk through a feeding tube until surgery is performed.

Surgical Intervention

The definitive treatment for pyloric stenosis is a surgical procedure called pyloromyotomy. This minimally invasive surgery involves making a small incision in the thickened pylorus muscle to allow food to pass through more easily.

Procedure Details

  • The surgery is typically performed laparoscopically, using small incisions and specialized instruments.
  • It is considered safe and effective, with most babies recovering quickly after the procedure.

Post-Surgery Care

After surgery, babies are monitored closely to ensure proper healing. Feeding is gradually reintroduced, starting with small amounts of formula or breast milk. Most infants can return to normal feeding routines within a few days.

Complications of Untreated Pyloric Stenosis

If left untreated, pyloric stenosis can lead to serious complications. These include:

Severe Dehydration

Chronic vomiting can result in significant fluid loss, leading to dehydration. Severe dehydration can be life-threatening and requires immediate medical attention.

Malnutrition

Without proper nutrient absorption, babies with pyloric stenosis are at risk of malnutrition. This can affect growth and development, causing long-term health issues.

Electrolyte Imbalance

Frequent vomiting can disrupt the balance of electrolytes in the body, such as sodium, potassium, and chloride. Electrolyte imbalances can lead to complications like heart rhythm abnormalities and muscle weakness.

Prevention and Outlook

While there is no guaranteed way to prevent pyloric stenosis, early recognition of symptoms and prompt medical care can significantly improve outcomes. With timely treatment, most babies recover fully and experience no long-term effects from the condition.

Prognosis

The prognosis for babies with pyloric stenosis is generally excellent. After successful surgery, most infants resume normal feeding patterns and achieve healthy growth and development.

Long-Term Follow-Up

Regular follow-up appointments with a pediatrician are important to monitor the baby’s recovery and overall health. Parents should report any ongoing symptoms or concerns to their healthcare provider promptly.

When to Seek Medical Attention

Parents and caregivers should seek immediate medical attention if they notice any of the following signs in their baby:

  • Forceful or projectile vomiting after feeding
  • Signs of dehydration, such as dry mouth, sunken eyes, or fewer wet diapers
  • Failure to gain weight or weight loss
  • Lethargy or unusual irritability

Early intervention can make a significant difference in the outcome for babies with pyloric stenosis.

Last Update: June 6, 2025