Peritonitis, often abbreviated as PT, is a serious medical condition characterized by inflammation of the peritoneum, the thin tissue lining the inner wall of the abdomen and covering the abdominal organs. This condition can be life-threatening if not treated promptly and effectively. Understanding its causes, recognizing its symptoms, and being aware of the diagnostic and treatment options are essential for managing this condition successfully. In this article, we will explore these aspects in detail to provide a comprehensive understanding of peritonitis.

What is Peritonitis?

The peritoneum serves as a protective barrier for the abdominal cavity, providing support to the organs within it. When this lining becomes inflamed due to infection or injury, it leads to a condition known as peritonitis. The inflammation can result from various factors, including bacterial infections, perforations in the gastrointestinal tract, or complications from other medical conditions. If left untreated, peritonitis can lead to severe complications such as sepsis, organ failure, and even death.

Causes of Peritonitis

There are two primary types of peritonitis: primary and secondary. Each type has distinct causes, which are outlined below:

Primary Peritonitis

  • Liver Disease: People with cirrhosis or other forms of liver disease are at an increased risk of developing primary peritonitis. This is because liver dysfunction can lead to the accumulation of fluid in the abdominal cavity, creating an environment where bacteria can thrive.
  • Weakened Immune System: Individuals with compromised immune systems, such as those undergoing chemotherapy or living with HIV/AIDS, are more susceptible to infections that can cause primary peritonitis.
  • Kidney Failure: Patients on peritoneal dialysis, a treatment for kidney failure, may develop primary peritonitis due to contamination during the dialysis process.

Secondary Peritonitis

  • Gastrointestinal Perforation: A hole or tear in the stomach, intestines, or other parts of the digestive system can allow bacteria from the gut to enter the abdominal cavity, leading to secondary peritonitis.
  • Ruptured Appendix: When the appendix bursts, it releases bacteria into the abdominal cavity, causing inflammation of the peritoneum.
  • Inflammatory Bowel Disease: Conditions like Crohn’s disease or ulcerative colitis can increase the risk of secondary peritonitis due to chronic inflammation and potential perforations in the intestinal walls.
  • Trauma or Surgery: Abdominal surgeries or injuries can introduce bacteria into the peritoneal cavity, resulting in secondary peritonitis.

Symptoms of Peritonitis

The symptoms of peritonitis can vary depending on the underlying cause and the severity of the condition. However, there are several common signs that individuals should be aware of:

  • Severe Abdominal Pain: One of the hallmark symptoms of peritonitis is intense pain in the abdomen. The pain is often described as sharp and may worsen with movement or touch.
  • Abdominal Swelling: The abdomen may appear swollen or distended due to the accumulation of fluid or gas.
  • Fever and Chills: An elevated body temperature and chills are common indicators of infection and inflammation.
  • Nausea and Vomiting: These symptoms often accompany peritonitis and can contribute to dehydration and weakness.
  • Many individuals with peritonitis experience a significant decrease in appetite.
  • Changes in bowel habits, including constipation or diarrhea, may occur.
  • An increased heart rate, also known as tachycardia, is a sign that the body is responding to infection or stress.
  • Some patients may experience reduced urine output, which can indicate dehydration or kidney involvement.

Diagnosis of Peritonitis

Diagnosing peritonitis requires a thorough evaluation by a healthcare professional. Several diagnostic tools and procedures are commonly used to confirm the presence of this condition:

Physical Examination

A doctor will begin by conducting a physical examination, paying close attention to the abdomen. Signs such as tenderness, rigidity, or rebound pain (pain that worsens when pressure is released) can suggest peritonitis.

Blood Tests

Blood tests are performed to check for elevated white blood cell counts, which indicate an infection. Additionally, blood cultures may be taken to identify the specific bacteria causing the infection.

Imaging Studies

  • Abdominal X-rays: These can help detect abnormalities such as free air in the abdominal cavity, which may indicate a perforation.
  • Ultrasound: This imaging technique is useful for identifying fluid buildup or abscesses in the abdomen.
  • Computed Tomography (CT) Scan: A CT scan provides detailed images of the abdominal organs and can help pinpoint the source of infection or inflammation.

Paracentesis

In cases where there is fluid accumulation in the abdomen, a procedure called paracentesis may be performed. During this procedure, a needle is inserted into the abdominal cavity to extract fluid, which is then analyzed for the presence of bacteria or other abnormalities.

Treatment Options for Peritonitis

The treatment of peritonitis depends on the underlying cause and the severity of the condition. Prompt intervention is critical to prevent complications and improve outcomes. The following are the main treatment approaches:

Antibiotics

Since bacterial infections are a common cause of peritonitis, antibiotics are a cornerstone of treatment. Broad-spectrum antibiotics are typically administered intravenously to target a wide range of bacteria. Once the specific bacteria are identified through laboratory tests, the antibiotic regimen may be adjusted accordingly.

Surgery

In cases of secondary peritonitis caused by perforations or ruptures, surgery is often necessary to repair the damage and remove any infected tissue. Common surgical procedures include:

  • Appendectomy: If a ruptured appendix is the cause, the appendix is surgically removed.
  • Bowel Repair: Tears or holes in the intestines may require surgical repair.
  • Drainage of Abscesses: If abscesses have formed, they may need to be drained to eliminate the source of infection.

Supportive Care

In addition to antibiotics and surgery, supportive care measures are essential for managing peritonitis:

  • Intravenous Fluids: Dehydration is common in patients with peritonitis, so fluids are administered intravenously to maintain hydration and stabilize blood pressure.
  • Pain Management: Medications such as analgesics are used to manage pain and discomfort.
  • Nutritional Support: In severe cases, patients may require nutritional support through a feeding tube or intravenous nutrition.

Monitoring and Follow-Up

After initial treatment, patients are closely monitored for signs of improvement or complications. Follow-up appointments and additional tests may be necessary to ensure that the infection has been fully resolved and to address any ongoing issues.

Prevention of Peritonitis

While not all cases of peritonitis can be prevented, certain measures can reduce the risk of developing this condition:

  • Proper Wound Care: Keeping surgical incisions and wounds clean and properly dressed can prevent infections that may lead to peritonitis.
  • Hygiene During Dialysis: Patients undergoing peritoneal dialysis should adhere to strict hygiene protocols to minimize the risk of contamination.
  • Timely Treatment of Infections: Promptly addressing infections in the abdomen or elsewhere in the body can prevent them from progressing to peritonitis.

Complications of Untreated Peritonitis

If peritonitis is not treated promptly, it can lead to severe complications, including:

  • Sepsis: A widespread infection that can result in organ failure and death.
  • Shock: A life-threatening condition characterized by dangerously low blood pressure.
  • Organ Damage: Prolonged inflammation can damage the abdominal organs, leading to long-term health issues.

Understanding the seriousness of peritonitis underscores the importance of seeking medical attention at the first sign of symptoms. Early diagnosis and treatment are crucial for improving outcomes and preventing complications.

Last Update: May 29, 2025