Erysipelas, also known as Saint Anthony’s Fire, is a bacterial skin infection that affects the upper layers of the skin. It is often characterized by its distinctive red, raised, and painful rash. Erysipelas can occur in people of all ages but is more common among older adults and those with weakened immune systems. Understanding this condition, including its causes, symptoms, and treatment options, is crucial for timely diagnosis and effective management.

Erysipelas: A Guide to Causes, Symptoms, and Treatments

What Is Erysipelas?

Erysipelas is an acute infection caused by bacteria entering the skin through cuts, wounds, or other breaks in the skin barrier. The infection primarily affects the dermis, which is the second layer of the skin, and may extend into the superficial lymphatic vessels. This leads to inflammation and the characteristic appearance of erysipelas.

The condition has been recognized for centuries and was historically referred to as “Saint Anthony’s Fire” due to the burning sensation experienced by those affected. Although medical advancements have improved our understanding of the disease, it remains a significant health concern, particularly for individuals with underlying health conditions.

Causes of Erysipelas

Erysipelas is most commonly caused by a specific type of bacteria called Streptococcus pyogenes. In rare cases, other types of streptococci or staphylococci may also be responsible for the infection. These bacteria thrive in warm, moist environments and can enter the body through small openings in the skin.

Common Entry Points for Bacteria

  • Cuts, scrapes, or abrasions on the skin
  • Insect bites or stings
  • Skin ulcers or open sores
  • Fungal infections such as athlete’s foot
  • Cracks in the skin caused by dryness or eczema

Risk Factors for Developing Erysipelas

While anyone can develop erysipelas, certain factors increase the likelihood of infection:

  • Weakened immune system due to conditions like diabetes, HIV, or cancer
  • Chronic skin conditions such as eczema or psoriasis
  • Lymphedema, which causes swelling in the arms or legs
  • Obesity, which can lead to skin folds that trap moisture
  • Recent surgery or injury to the skin
  • Poor circulation or venous insufficiency

Symptoms of Erysipelas

The symptoms of erysipelas typically develop quickly and are often severe. Recognizing these signs early can help prevent complications and ensure prompt treatment.

Early Signs

In the early stages, erysipelas may present with the following symptoms:

  • A sudden onset of fever and chills
  • Fatigue and general malaise
  • Swollen lymph nodes near the affected area

Characteristic Skin Changes

As the infection progresses, distinct changes occur in the skin:

  • A bright red, shiny rash that feels warm to the touch
  • Sharp borders between the infected and healthy skin
  • Raised, swollen areas that may feel firm
  • Burning or itching sensation in the affected region
  • Blisters or skin peeling in severe cases

Common Locations

Erysipelas most frequently occurs on the legs, particularly the lower legs, but it can also affect other parts of the body:

  • Face, especially the cheeks and nose
  • Arms and hands
  • Torso in rare instances

Diagnosis of Erysipelas

Diagnosing erysipelas typically involves a physical examination and a review of the patient’s medical history. Healthcare providers look for the hallmark signs of the infection, such as the red, raised rash with well-defined borders.

Differential Diagnosis

Because erysipelas shares symptoms with other skin conditions, healthcare professionals must rule out similar diseases, including:

  • Cellulitis, which affects deeper layers of the skin
  • Deep vein thrombosis, which causes leg swelling and pain
  • Contact dermatitis, an allergic reaction to irritants
  • Herpes zoster, also known as shingles

Additional Tests

In some cases, additional tests may be necessary to confirm the diagnosis or identify the specific bacteria causing the infection:

  • Blood tests to check for elevated white blood cell counts
  • Culture of fluid from blisters or open sores
  • Imaging studies, such as ultrasound, to assess the extent of the infection

Treatment Options for Erysipelas

Treatment for erysipelas focuses on eliminating the bacterial infection, reducing symptoms, and preventing recurrence. Early intervention is key to avoiding complications.

Antibiotic Therapy

The primary treatment for erysipelas is antibiotics, which are usually administered orally. Commonly prescribed antibiotics include:

  • Penicillin, which is highly effective against streptococcal infections
  • Erythromycin, an alternative for patients allergic to penicillin
  • Cephalexin, a broad-spectrum antibiotic

In severe cases, hospitalization may be required, and intravenous antibiotics may be administered to ensure faster recovery.

Pain Management

To alleviate discomfort, over-the-counter pain relievers such as acetaminophen or ibuprofen may be recommended. Applying cool compresses to the affected area can also help reduce swelling and soothe the skin.

Wound Care

Proper wound care is essential to prevent further infection:

  • Keep the affected area clean and dry
  • Elevate the limb if the infection is on the leg or arm
  • Avoid scratching or picking at blisters

Preventing Recurrence

Individuals who experience recurrent episodes of erysipelas may require long-term preventive measures:

  • Low-dose antibiotics taken daily for several months
  • Regular monitoring and treatment of underlying conditions like lymphedema
  • Maintaining good skin hygiene and moisturizing to prevent cracks

Potential Complications of Erysipelas

If left untreated, erysipelas can lead to serious complications that affect both the skin and internal organs. Awareness of these risks underscores the importance of seeking medical attention promptly.

Localized Complications

Complications that occur at the site of infection include:

  • Abscess formation, which requires surgical drainage
  • Necrosis, or tissue death, in severe cases
  • Permanent scarring or changes in skin texture

Systemic Complications

In rare cases, the infection can spread beyond the skin and cause systemic issues:

  • Bacteremia, where bacteria enter the bloodstream
  • Septic shock, a life-threatening condition
  • Kidney damage due to prolonged infection

Lifestyle Tips for Managing Erysipelas

In addition to medical treatment, lifestyle modifications can play a significant role in managing erysipelas and reducing the risk of recurrence.

Healthy Skin Practices

Maintaining healthy skin is critical for preventing infections:

  • Moisturize regularly to prevent dryness and cracking
  • Treat fungal infections promptly to avoid secondary bacterial infections
  • Wear protective clothing when engaging in activities that may cause skin injuries

Diet and Immune Support

A balanced diet rich in vitamins and minerals supports overall immune function:

  • Include foods high in vitamin C, such as citrus fruits and leafy greens
  • Stay hydrated to promote skin health
  • Avoid excessive alcohol consumption and smoking

Exercise and Circulation

Improving circulation can reduce the risk of developing conditions like lymphedema:

  • Engage in regular physical activity, such as walking or swimming
  • Elevate the legs periodically to reduce swelling
  • Use compression stockings if recommended by a healthcare provider

Last Update: April 25, 2025