Vulvar cancer, often abbreviated as VC, is a rare type of cancer that affects the external female genitalia. It accounts for a small percentage of all gynecological cancers but remains a significant health concern due to its potential impact on quality of life. This article provides an in-depth look at the types, symptoms, diagnosis, and treatment options available for this condition.

Vulvar Cancer: Types, Symptoms, Diagnosis, and Treatment

Understanding Vulvar Cancer

Vulvar cancer occurs when abnormal cells grow uncontrollably in the vulva, which includes the inner and outer lips of the vagina, the clitoris, and the opening of the vagina. While it is most commonly diagnosed in older women, it can affect individuals of any age. Understanding the different types of this cancer is crucial for early detection and effective management.

Types of Vulvar Cancer

There are several types of vulvar cancer, each originating from different types of cells within the vulva. The most common types include:

  • Squamous Cell Carcinoma: This is the most prevalent form, accounting for approximately ninety percent of all cases. It begins in the thin, flat cells that line the surface of the vulva.
  • Adenocarcinoma: This type starts in the glandular cells of the vulva, which are responsible for producing mucus and other fluids.
  • Melanoma: A less common but aggressive form of cancer that develops in the pigment-producing cells of the skin.
  • Sarcoma: This rare type originates in the connective tissue of the vulva, such as muscles or fat.
  • Basal Cell Carcinoma: Another uncommon type, it arises from the basal cells located in the deepest layer of the skin.

Symptoms of Vulvar Cancer

Recognizing the symptoms of vulvar cancer is essential for timely intervention. However, it is important to note that some symptoms may overlap with other, less serious conditions. Common signs to watch for include:

  • Persistent itching in the vulvar area
  • Pain or tenderness in the vulva
  • A noticeable lump, bump, or ulceration on the vulva
  • Changes in the color or texture of the skin on the vulva
  • Bleeding from the vulva not associated with menstruation
  • Pain during sexual intercourse or urination

If any of these symptoms persist for more than a few weeks, it is advisable to consult a healthcare provider for further evaluation.

Diagnosing Vulvar Cancer

Diagnosing vulvar cancer typically involves a combination of physical examinations, laboratory tests, and imaging studies. Early diagnosis improves the chances of successful treatment. Below are the key steps involved in diagnosing this condition:

Physical Examination

The first step in diagnosing vulvar cancer is a thorough physical examination. A healthcare provider will visually inspect the vulva for any abnormalities, such as lumps, sores, or discoloration. They may also perform a pelvic exam to check for additional signs of cancer.

Biopsy

If an abnormal area is detected during the physical exam, a biopsy is usually performed. During this procedure, a small sample of tissue is removed from the affected area and sent to a laboratory for analysis. The biopsy helps confirm the presence of cancer and determines its type and stage.

Imaging Tests

In some cases, imaging tests may be recommended to determine whether the cancer has spread beyond the vulva. These tests may include:

  • Magnetic Resonance Imaging (MRI): Provides detailed images of the vulva and surrounding tissues.
  • Computed Tomography (CT) Scan: Helps identify the extent of cancer spread to nearby lymph nodes or organs.
  • Pet Scan: Detects cancerous activity throughout the body by highlighting areas with high metabolic activity.

Cystoscopy and Proctoscopy

In advanced cases, additional procedures such as cystoscopy (examination of the bladder) or proctoscopy (examination of the rectum) may be conducted to assess whether the cancer has invaded nearby structures.

Treatment Options for Vulvar Cancer

Treatment for vulvar cancer depends on various factors, including the type and stage of the cancer, the patient’s overall health, and personal preferences. A multidisciplinary approach involving surgeons, oncologists, and other specialists is often employed to develop a personalized treatment plan. The primary treatment options include:

Surgery

Surgical intervention is the most common treatment for vulvar cancer. The type of surgery performed depends on the size and location of the tumor, as well as whether the cancer has spread. Common surgical procedures include:

  • Excision: Removal of the cancerous tissue along with a margin of healthy tissue to ensure complete eradication.
  • Vulvectomy: Partial or complete removal of the vulva, depending on the extent of the cancer.
  • Removal of lymph nodes in the groin area to check for cancer spread.

Radiation Therapy

Radiation therapy uses high-energy beams to destroy cancer cells. It may be used before surgery to shrink tumors or after surgery to eliminate any remaining cancer cells. In some cases, radiation therapy is combined with chemotherapy for enhanced effectiveness.

Chemotherapy

Chemotherapy involves the use of drugs to kill cancer cells. It is often administered intravenously or orally and may be recommended if the cancer has spread to other parts of the body. Chemotherapy is sometimes used in conjunction with radiation therapy for advanced cases.

Targeted Therapy

Targeted therapy focuses on specific molecules or pathways involved in cancer growth. Unlike traditional chemotherapy, targeted therapy tends to have fewer side effects because it spares healthy cells. This option is typically reserved for certain types of vulvar cancer, such as melanoma.

Immunotherapy

Immunotherapy harnesses the body’s immune system to fight cancer. It is particularly useful for treating advanced or recurrent vulvar cancer. By boosting the immune response, immunotherapy can help slow or stop the progression of the disease.

Lifestyle and Supportive Care

In addition to medical treatments, supportive care plays a vital role in managing vulvar cancer. Patients are encouraged to adopt a healthy lifestyle, including a balanced diet, regular exercise, and adequate rest. Emotional support from family, friends, and support groups can also help patients cope with the challenges of cancer treatment.

Palliative Care

Palliative care focuses on relieving symptoms and improving the quality of life for patients with advanced cancer. It may include pain management, nutritional support, and counseling services. Palliative care can be provided alongside curative treatments to address both physical and emotional needs.

Follow-Up Care

Regular follow-up appointments are essential after completing treatment for vulvar cancer. These visits allow healthcare providers to monitor recovery, manage side effects, and detect any signs of recurrence early. Follow-up care may include physical exams, imaging tests, and discussions about ongoing health concerns.

Last Update: June 25, 2025